Factors affecting glycemic control in patients with type 2 diabetes mellitus using oral antidiabetics: A single-center experience

Abstract

In this retrospective study, we aimed to investigate the factors affecting glycemic control in patients with type 2 diabetes mellitus (DM) treated with oral antidiabetic drugs (OADs). From 2019 to 2020, type 2 DM patients treated with OADs were included in this study. Patients less than 18 years old and those treated with insulin were excluded from the study. The patients were divided into two groups according to HbA1C levels as follows: good glycemic control (GGC) (<7%) or poor glycemic control (PGC) (≥7). Of the 505 type 2 DM patients, 270 (53.5%) were female. There were 194 (38.4%) patients in the GGC group and 311 (61.6%) in the PGC group. The rate of marriage and employment were higher in the GGC group than those in the PGC group. Likewise, education level and, and high-density lipoprotein were higher in the GGC group than those in the PGC group. In the multivariate analysis, being married (odds ratio [OR], 0.39), duration of DM (OR, 1.12), having a high-school graduate (OR, 0.43), triglyceride level (OR, 1.001), and high-density lipoprotein level (OR, 0.979) were the factors affecting glycemic control. In this study, we found that being married and having a higher education level and high-density lipoprotein level were associated with GGC in type 2 DM patients treated with OADs.

Key words: Glycemic control, oral antidiabetic drugs, marital status, body mass index